![]() Incidence was highest in children aged between 3 and 17 (highest mean incidence of 29 cases/100,000 inhabitants in 6–9 year olds) with a second peak in 60–79 year old individuals. Age-specific incidence showed male predominance and a bimodal distribution. Also specific differences in the disease pattern of adolescents and adults became obvious. ![]() Cases tended to accumulate between June and September with remarkable changes in disease manifestations in the course of the year documented in the coded secondary diagnoses. The annual indirect costs due to loss of productivity would add up to more than 7 million Euro as assessed by the human capital method. Based on extrapolation of our findings to the German population, we would expect an average hospital admission of 5200 adults and 2300 adolescents (<18 years) for LB treatment incurring direct medical costs of more than 23 million Euro annually. The median inpatient time was 9 days resulting in a median direct medical cost per hospital stay of 3917€ for adolescents and 2843€ for adults. In our cohort the incident diagnosis of LB was coded for 2163 inpatient cases during the years 2008–2011. Total cost was calculated for a 1-year period both from the third-party payers and from the societal perspective, respectively. This retrospective analysis is based on data provided for the years 2007–2011 by a German statutory health insurance company (DAK-Gesundheit) covering approximately 6 million insured. To date, relatively little is known about the economic and medical impact of Lyme borreliosis (LB) on European health care systems, especially for the inpatient sector. ![]()
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